Rebecca H Ritchie Selected Research

Diabetic Cardiomyopathies

4/2022	Cellular interplay between cardiomyocytes and non-myocytes in diabetic cardiomyopathy.
1/2022	The adiponectin signalling pathway - A therapeutic target for the cardiac complications of type 2 diabetes?
1/2022	Fine-tuning the cardiac O-GlcNAcylation regulatory enzymes governs the functional and structural phenotype of the diabetic heart.
11/2021	Adeno-associated viral (AAV) vector-mediated therapeutics for diabetic cardiomyopathy - current and future perspectives.
1/2021	Bone Morphogenetic Protein 7 Gene Delivery Improves Cardiac Structure and Function in a Murine Model of Diabetic Cardiomyopathy.
12/2019	The Mitochondria-Targeted Methylglyoxal Sequestering Compound, MitoGamide, Is Cardioprotective in the Diabetic Heart.
6/2017	Phosphoinositide 3-kinase (p110α) gene delivery limits diabetes-induced cardiac NADPH oxidase and cardiomyopathy in a mouse model with established diastolic dysfunction.
5/2017	Are targeted therapies for diabetic cardiomyopathy on the horizon?
1/2017	Insulin replacement limits progression of diabetic cardiomyopathy in the low-dose streptozotocin-induced diabetic rat.
1/2017	Insights into the role of maladaptive hexosamine biosynthesis and O-GlcNAcylation in development of diabetic cardiac complications.

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Rebecca H Ritchie Research Topics

Disease

17	Hypertrophy 01/2021 - 10/2002
16	Diabetic Cardiomyopathies 04/2022 - 06/2010
14	Fibrosis (Cirrhosis) 01/2022 - 06/2010
11	Heart Failure 01/2022 - 06/2014
11	Cardiomyopathies (Cardiomyopathy) 01/2022 - 02/2010
11	Inflammation (Inflammations) 01/2021 - 01/2017
11	Insulin Resistance 02/2020 - 01/2006
9	Cardiomegaly (Heart Hypertrophy) 06/2015 - 09/2003
7	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 01/2017
7	Hyperglycemia 01/2020 - 06/2011
6	Left Ventricular Dysfunction 01/2022 - 06/2014
6	Type 2 Diabetes Mellitus (MODY) 01/2022 - 02/2012
6	Reperfusion Injury 01/2019 - 04/2015
5	Hypertension (High Blood Pressure) 01/2021 - 07/2010
5	Heart Diseases (Heart Disease) 01/2017 - 04/2003
4	Body Weight (Weight, Body) 01/2021 - 06/2015
4	Ischemia 01/2021 - 01/2003
4	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 07/2017 - 04/2008
3	Diabetes Complications 01/2021 - 01/2017
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 02/2012
3	Glucose Intolerance 01/2021 - 06/2011
3	Diabetes Mellitus 01/2020 - 05/2015
3	Myocardial Infarction 01/2020 - 01/2018
3	Myocardial Ischemia (Ischemic Heart Diseases) 01/2019 - 09/2006
2	Peripheral Arterial Disease 01/2021 - 01/2021
2	Cardiac Arrhythmias (Arrythmia) 01/2021 - 01/2021
2	Stroke (Strokes) 01/2019 - 01/2018
2	Diabetic Nephropathies (Diabetic Nephropathy) 07/2017 - 02/2012
2	Myocardial Reperfusion Injury 01/2017 - 01/2013
1	Obesity 01/2022
1	Atherosclerotic Plaque (Atheroma) 01/2022
1	Vascular Diseases (Vascular Disease) 01/2021
1	Atherosclerosis 01/2021
1	Ventricular Dysfunction 01/2021

Drug/Important Bio-Agent (IBA)

10	Superoxides (Superoxide)IBA 01/2021 - 10/2006
10	Streptozocin (Streptozotocin)FDA Link 01/2021 - 04/2008
9	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2003
7	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021 - 10/2002
7	Insulin (Novolin)FDA Link 01/2019 - 02/2010
7	AntioxidantsIBA 07/2017 - 01/2007
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2010
6	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 02/2010
6	FructoseIBA 12/2016 - 05/2010
5	Blood Glucose (Blood Sugar)IBA 01/2021 - 06/2015
5	nitroxylIBA 01/2020 - 01/2012
5	NADPH Oxidases (NAD(P)H oxidase)IBA 07/2017 - 01/2012
4	CollagenIBA 01/2020 - 06/2015
3	CytokinesIBA 01/2021 - 07/2017
3	Angiotensin IIIBA 01/2019 - 09/2004
3	Peptides (Polypeptides)IBA 01/2019 - 01/2003
3	Atrial Natriuretic Factor (ANF)IBA 10/2015 - 02/2003
3	coenzyme Q10 (CoQ10)IBA 10/2015 - 02/2012
3	Cyclic GMPIBA 09/2003 - 10/2002
2	SugarsIBA 01/2022 - 05/2010
2	InflammasomesIBA 01/2021 - 01/2018
2	NLR ProteinsIBA 01/2021 - 01/2018
2	ResveratrolIBA 01/2021 - 01/2007
2	Nicotine FDA Link 01/2021 - 01/2019
2	Pharmaceutical PreparationsIBA 01/2021 - 01/2021
2	HexosaminesIBA 01/2020 - 01/2017
2	ProstaglandinsIBA 01/2020 - 09/2004
2	RelaxinIBA 01/2020 - 01/2018
2	EnzymesIBA 01/2020 - 12/2016
2	Thrombin FDA Link 01/2019 - 10/2014
2	CalciumIBA 01/2019 - 01/2017
2	MicroRNAs (MicroRNA)IBA 01/2018 - 06/2014
2	Metalloproteases (Metalloproteinases)IBA 01/2018 - 05/2011
2	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 01/2018 - 01/2017
2	Ramipril (Altace)FDA LinkGeneric 07/2017 - 07/2013
2	tempolIBA 07/2017 - 10/2006
2	Phosphatidylinositols (Phosphatidylinositol)IBA 06/2017 - 10/2015
2	LipidsIBA 01/2017 - 06/2015
2	Dietary SugarsIBA 12/2016 - 02/2010
2	UbiquinoneIBA 10/2015 - 02/2012
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 07/2013 - 09/2003
2	Citric Acid (Citrate)FDA LinkGeneric 07/2013 - 04/2008
2	LigandsIBA 01/2012 - 05/2011
2	Soluble Guanylyl CyclaseIBA 01/2012 - 01/2012
2	Phenylalanine (L-Phenylalanine)FDA Link 09/2004 - 02/2003
2	Messenger RNA (mRNA)IBA 09/2004 - 02/2003
2	BradykininIBA 09/2003 - 10/2002
2	GuanosineIBA 09/2003 - 10/2002
1	Sodium-Glucose Transport ProteinsIBA 04/2022
1	AdipokinesIBA 01/2022
1	AcetylglucosamineIBA 01/2022
1	AdiponectinIBA 01/2022
1	N-propionylprocainamideIBA 01/2022
1	Adiponectin ReceptorsIBA 01/2022
1	Peroxynitrous Acid (Peroxynitrite)IBA 01/2021
1	MitoTEMPOIBA 01/2021
1	Hydroxyl RadicalIBA 01/2021
1	N- (1,2,3,5,6,7- hexahydro- S- indacen- 4- ylcarbamoyl)- 4- (2- hydroxy- 2- propanyl)- 2- furansulfonamideIBA 01/2021
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2021
1	Bone Morphogenetic Protein 7IBA 01/2021
1	ApolipoproteinsIBA 01/2021
1	LipoxinsIBA 02/2020
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 02/2020

Therapy/Procedure

16	Therapeutics 04/2022 - 12/2009
6	Drug Therapy (Chemotherapy) 01/2021 - 09/2009
1	Surgical Amputation (Amputations) 01/2022